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pubmed-article:19909293pubmed:abstractTextChondrocytes inevitably decrease production of cartilaginous matrices during long-term cultures with repeated passaging; this is termed dedifferentiation. To learn more concerning prevention of dedifferentiation, we have focused here on the fibroblast growth factor (FGF) family that influences chondrocyte proliferation or differentiation.lld:pubmed
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pubmed-article:19909293pubmed:articleTitleInvolvement of fibroblast growth factor 18 in dedifferentiation of cultured human chondrocytes.lld:pubmed
pubmed-article:19909293pubmed:affiliationDepartment of Cartilage, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.lld:pubmed
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