rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2010-1-14
|
pubmed:abstractText |
Chondrocytes inevitably decrease production of cartilaginous matrices during long-term cultures with repeated passaging; this is termed dedifferentiation. To learn more concerning prevention of dedifferentiation, we have focused here on the fibroblast growth factor (FGF) family that influences chondrocyte proliferation or differentiation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/COL2A1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type I,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Fibroblast Growth Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Fibroblast Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta,
http://linkedlifedata.com/resource/pubmed/chemical/collagen type I, alpha 1 chain,
http://linkedlifedata.com/resource/pubmed/chemical/fibroblast growth factor 18
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1365-2184
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
67-76
|
pubmed:meshHeading |
pubmed-meshheading:19909293-Cell Dedifferentiation,
pubmed-meshheading:19909293-Cells, Cultured,
pubmed-meshheading:19909293-Chondrocytes,
pubmed-meshheading:19909293-Collagen Type I,
pubmed-meshheading:19909293-Collagen Type II,
pubmed-meshheading:19909293-Fibroblast Growth Factors,
pubmed-meshheading:19909293-Gene Expression Profiling,
pubmed-meshheading:19909293-Humans,
pubmed-meshheading:19909293-Ligands,
pubmed-meshheading:19909293-RNA, Small Interfering,
pubmed-meshheading:19909293-Receptors, Fibroblast Growth Factor,
pubmed-meshheading:19909293-Transforming Growth Factor beta
|
pubmed:year |
2010
|
pubmed:articleTitle |
Involvement of fibroblast growth factor 18 in dedifferentiation of cultured human chondrocytes.
|
pubmed:affiliation |
Department of Cartilage, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|