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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1 Pt 1
|
| pubmed:dateCreated |
1991-3-5
|
| pubmed:abstractText |
The lung was investigated as a matrix for transplanted hepatocytes in the rat model. Surgically induced fulminant hepatic failure was successfully treated by injection of 5 to 7 x 10(7) isolated hepatocytes into the pulmonary parenchyma in 86% of the animals. No animal, however, survived injection of hepatocytes into the jugular vein. It was found that liver failure is a prerequisite for the intrapulmonary survival of hepatocytes. After regeneration of the native liver, the majority of hepatocytes are cleared away within 6 months.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0041-1345
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
892-3
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1990717-Acute Disease,
pubmed-meshheading:1990717-Animals,
pubmed-meshheading:1990717-Cell Separation,
pubmed-meshheading:1990717-Hepatectomy,
pubmed-meshheading:1990717-Liver,
pubmed-meshheading:1990717-Liver Diseases,
pubmed-meshheading:1990717-Liver Transplantation,
pubmed-meshheading:1990717-Lung,
pubmed-meshheading:1990717-Male,
pubmed-meshheading:1990717-Rats,
pubmed-meshheading:1990717-Rats, Inbred Lew,
pubmed-meshheading:1990717-Transplantation, Heterotopic
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Hepatocyte transplantation into the lung for treatment of acute hepatic failure in the rat.
|
| pubmed:affiliation |
Department of Transplant Surgery, University Hospital, Innsbruck, Austria.
|
| pubmed:publicationType |
Journal Article
|