Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-11-9
pubmed:abstractText
Aqueous extract of the roots of Radix paeoniae (Paeonaceae) was screened for wound healing by excision, incision and dead space wound models on Wistar rats. The parameters studied were breaking strength in case of incision wounds, epithelialisation and wound contraction in case of excision wound and granulation tissue dry weight, breaking strength and hydroxyproline content in case of dead space wound. The Nitrofurazone ointment treated group showed a significant (p < 0.001) reduction in the wound breaking strength when compared to control group in incision type of wound model. The results obtained indicated that Radix paeoniae root extract accelerates the wound healing process by decreasing the surface area of the wound and increasing the tensile strength. The histological examination of the granulation tissue of treated group showed increased cross-linking of collagen fibers and absence of monocytes.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6837
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
543-7
pubmed:dateRevised
2010-1-6
pubmed:meshHeading
pubmed:articleTitle
Wound healing activity of aqueous extract of Radix paeoniae root.
pubmed:affiliation
Department of Pharmacognosy, Smriti College of Pharmaceutical Education, Dewas Naka, Indore-452010 Madhya Pradesh, India. neelesh_brncop@rediffmail.com
pubmed:publicationType
Journal Article, Comparative Study