Linked Life Data

19887926

Source:http://linkedlifedata.com/resource/pubmed/id/19887926

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-11-25
pubmed:abstractText
The aim of this study was to examine the effects of negative pressure wound therapy (NPWT) on wound edge microvascular blood flow, comparing different wound fillers. Wounds were created on the backs of 7 pigs. NPWT was applied, using either foam or gauze, at -50,-75, -100, -125, -150, or -175 mm Hg. Microvascular blood flow was measured in muscle tissue, subcutaneous tissue, and in the wound bed, at 0.5, 1, and 2.5 cm from the wound edge, using laser Doppler velocimetry. Similar patterns of blood flow response were observed when using foam or gauze. At 2.5 cm from the wound edge there was an increase in microvascular blood flow, while blood flow was decreased closer (0.5 cm) to the wound edge. The blood flow effects were similar at the different levels of negative pressure in muscle tissue, subcutaneous tissue, and in the wound bed. Altered microvascular blood flow to the wound edge may be one of the mechanisms by which NPWT facilitates healing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1536-3708
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
676-81
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Wound edge microvascular blood flow: effects of negative pressure wound therapy using gauze or polyurethane foam.
pubmed:affiliation
Department of Ophthalmology, Lund University Hospital, Lund, Sweden. malin.malmsjo@med.lu.se
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't