| pubmed-article:1988227 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0010453 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0021760 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0026473 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0227651 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0596290 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:1988227 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:1988227 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1988227 | pubmed:dateCreated | 1991-2-22 | lld:pubmed |
| pubmed-article:1988227 | pubmed:abstractText | Conditioned media from human peripheral blood leucocytes treated with lipopolysaccharide (LPS) induced a marked increase in the 3H-thymidine incorporation of cultured mesangial cells at low serum concentration (four to six times higher than control). Two sizes (100-70 and 8-12 kD) of monocyte-derived mesangial cell proliferating factors (MDF) were separated by column chromatography. Their peaks were distinct from those of thymocyte proliferating activity. The addition of anti-human interleukin-1 (IL-1) or anti-recombinant human interleukin-6 (IL-6) antibody to the fractionated MDF failed to have any effect on the mitogenic activity toward mesangial cells. The addition of anti-human platelet-derived growth factor (PDGF) antibody to the low molecular weight fraction decreased mesangial cell mitogenic activity (40-60% of control), but addition to the higher fraction did not (80-100% of control). From these data it seems that a large portion of the monocyte-derived mesangial cell growth factor was not comprised of IL-1 or IL-6 but of PDGF-like molecules; and that there is an unknown mesangial cell proliferating factor (or factors) besides IL-1, IL-6 and PDGF. | lld:pubmed |
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| pubmed-article:1988227 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1988227 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1988227 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1988227 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:1988227 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1988227 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1988227 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:1988227 | pubmed:author | pubmed-author:ShimizuFF | lld:pubmed |
| pubmed-article:1988227 | pubmed:author | pubmed-author:MoriokaTT | lld:pubmed |
| pubmed-article:1988227 | pubmed:author | pubmed-author:OiteTT | lld:pubmed |
| pubmed-article:1988227 | pubmed:author | pubmed-author:NaritaII | lld:pubmed |
| pubmed-article:1988227 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1988227 | pubmed:volume | 83 | lld:pubmed |
| pubmed-article:1988227 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1988227 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1988227 | pubmed:pagination | 182-6 | lld:pubmed |
| pubmed-article:1988227 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1988227 | pubmed:meshHeading | pubmed-meshheading:1988227-... | lld:pubmed |
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| pubmed-article:1988227 | pubmed:meshHeading | pubmed-meshheading:1988227-... | lld:pubmed |
| pubmed-article:1988227 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1988227 | pubmed:articleTitle | Production by cultured human monocytes of mesangial cell proliferation factor(s) differing from interleukin-1 and interleukin-6. | lld:pubmed |
| pubmed-article:1988227 | pubmed:affiliation | Department of Immunology, Niigata University School of Medicine, Japan. | lld:pubmed |
| pubmed-article:1988227 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1988227 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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