Linked Life Data

1987866

Source:http://linkedlifedata.com/resource/pubmed/id/1987866

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-2-20
pubmed:abstractText
A two-site immunoassay using monoclonal antibodies has been developed to measure the imported fire ant venom allergen Sol i III. The assay is specific for Solenopsis invicta venom, since one of the monoclonal antibodies does not react with Sol r III. A commercial imported fire ant whole body extract, known from RAST and skin test data to be potent, was found to contain 10.3 micrograms of Sol i III per milliliter. This was comparable to the content of an extract freshly prepared in our laboratory. The immunoassay detected Sol i III in an extract of fire ant abdomens, but not in head and thorax extract. The amount of imported fire ant venom in a potent whole body extract appears to be sufficient to provide possible protection for patients receiving it as immunotherapy, although this can only be verified by controlled clinical trials with intentional sting challenges.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-4738
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-31
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Allergens in Hymenoptera venoms. XXIII. Venom content of imported fire ant whole body extracts.
pubmed:affiliation
Department of Pathology, East Carolina University School of Medicine, Greenville, North Carolina.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.