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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-11-2
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pubmed:abstractText |
Immune thrombocytopenic purpura (ITP) is a bleeding disorder characterized by an accelerated destruction of platelets as a result of the presence of autoreactive antibodies. Patients with ITP also display activated platelet-autoreactive T cells. Mesenchymal stem cells (MSC) inhibit both T- and B-cell activation and may have functional impairments in autoimmune disorders.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1477-2566
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pubmed:author |
pubmed-author:AlbercaIgnacioI,
pubmed-author:BlancoBelénB,
pubmed-author:CañizoConsueloC,
pubmed-author:CanchadoJavierJ,
pubmed-author:Díez-CampeloMaríaM,
pubmed-author:Herrero-SánchezCarmenC,
pubmed-author:Pérez-SimónJose AntonioJA,
pubmed-author:Sánchez-AbarcaLuis IgnacioLI,
pubmed-author:San MiguelJesús FJF,
pubmed-author:SarasqueteMaría EugeniaME,
pubmed-author:TaberaSorayaS
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
698-705
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pubmed:meshHeading |
pubmed-meshheading:19878056-Adult,
pubmed-meshheading:19878056-Autoantibodies,
pubmed-meshheading:19878056-B-Lymphocytes,
pubmed-meshheading:19878056-Caspase 9,
pubmed-meshheading:19878056-Cell Cycle,
pubmed-meshheading:19878056-Cell Differentiation,
pubmed-meshheading:19878056-Cell Proliferation,
pubmed-meshheading:19878056-Cyclin-Dependent Kinase Inhibitor p16,
pubmed-meshheading:19878056-Humans,
pubmed-meshheading:19878056-Lymphocyte Activation,
pubmed-meshheading:19878056-Mesenchymal Stem Cells,
pubmed-meshheading:19878056-Middle Aged,
pubmed-meshheading:19878056-Platelet-Derived Growth Factor,
pubmed-meshheading:19878056-Purpura, Thrombocytopenic, Idiopathic,
pubmed-meshheading:19878056-T-Lymphocytes
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pubmed:year |
2009
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pubmed:articleTitle |
Mesenchymal stem cells are functionally abnormal in patients with immune thrombocytopenic purpura.
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pubmed:affiliation |
Servicio de Hematología, Hospital Clínico Universitario y Centro de Investigación del Cáncer de Salamanca, Spain. pesimop@usal.es
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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