Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1991-2-15
|
pubmed:abstractText |
Regional cerebral perfusion was studied in three patients with the mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome, using single photon emission computed tomography (SPECT) with N-isopropyl-p-[123I]iodoamphetamine (IMP). Accumulation of the tracer was relatively decreased in the parietooccipital regions and also in the frontotemporal regions after stroke-like episodes. However, quantitative regional cerebral blood flow (rCBF) measurement showed that rCBF was relatively well preserved even at these sites, and a hyperemic state was observed at the sites of normal accumulation. IMP SPECT may be useful in the diagnosis and assessment of the progress of the MELAS syndrome.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0363-8715
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
77-82
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1987205-Acidosis, Lactic,
pubmed-meshheading:1987205-Adolescent,
pubmed-meshheading:1987205-Adult,
pubmed-meshheading:1987205-Amphetamines,
pubmed-meshheading:1987205-Brain Diseases,
pubmed-meshheading:1987205-Cerebrovascular Disorders,
pubmed-meshheading:1987205-Female,
pubmed-meshheading:1987205-Humans,
pubmed-meshheading:1987205-Iodine Radioisotopes,
pubmed-meshheading:1987205-Iofetamine,
pubmed-meshheading:1987205-Magnetic Resonance Imaging,
pubmed-meshheading:1987205-Male,
pubmed-meshheading:1987205-Mitochondria, Muscle,
pubmed-meshheading:1987205-Muscular Diseases,
pubmed-meshheading:1987205-Syndrome,
pubmed-meshheading:1987205-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:1987205-Tomography, X-Ray Computed
|
pubmed:articleTitle |
N-isopropyl-p-[123I]iodoamphetamine SPECT in MELAS syndrome: comparison with CT and MR imaging.
|
pubmed:affiliation |
Department of Radiology, University of Tsukuba, Japan.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Case Reports
|