Linked Life Data

19869847

Source:http://linkedlifedata.com/resource/pubmed/id/19869847

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2010-6-23
pubmed:abstractText
The above experiments demonstrate that guinea pigs and rats subjected to vitamin-deficient diets to a point at which deficiency symptoms appear, and then inoculated with typhus virus, exhibit clinical pictures which indicate a far more severe infection than that observed in normal animals after inoculation. There is also a wider distribution of Rickettsiae and a concentration of organisms which, in pleural and peritoneal exudates, amounts to almost cultural proportions. Important from our point of view is the fact that these experiments furnished a step toward the accomplishment of our purpose, which was to obtain amounts and concentrations of Rickettsiae suitable for immunological studies until such a time when tissue culture may have developed to a practically useful stage. The experiments are of immediate importance in that they furnish us a method for improving our technique of active immunization reported upon in the preceding paper, No. V (8). From the epidemiological point of view these experiments at least suggest an explanation of one of the important factors which enter into the historical association of high typhus mortality with war and famine.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Feb
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
333-8
pubmed:dateRevised
2010-9-28
pubmed:year
1931
pubmed:articleTitle
STUDIES ON TYPHUS FEVER : VI. REDUCTION OF RESISTANCE BY DIET DEFICIENCY.
pubmed:affiliation
Department of Bacteriology and Immunology, Harvard University Medical School, Boston.
pubmed:publicationType
Journal Article