Source:http://linkedlifedata.com/resource/pubmed/id/19844814
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2010-10-19
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pubmed:abstractText |
Polycystic ovary syndrome (PCOS) is a complex multifactorial disorder involving a number of genetic and environmental factors. Adipocyte-fatty acid-binding protein (FABP4) is an adipokine regulating systemic insulin sensitivity, lipid and glucose metabolism. In humans serum FABP4 levels correlate significantly with features of PCOS. Previous researches showed strong evidences that FABP4 impacted the developing of PCOS possibly through its protein alteration or transcription regulation. Thus, the present study is the first attempt to identify the possible genetic role of FABP4 gene in the development of PCOS.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1559-0100
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
392-6
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pubmed:meshHeading |
pubmed-meshheading:19844814-Adult,
pubmed-meshheading:19844814-Body Mass Index,
pubmed-meshheading:19844814-Case-Control Studies,
pubmed-meshheading:19844814-Fatty Acid-Binding Proteins,
pubmed-meshheading:19844814-Female,
pubmed-meshheading:19844814-Gene Frequency,
pubmed-meshheading:19844814-Genetic Association Studies,
pubmed-meshheading:19844814-Genetic Predisposition to Disease,
pubmed-meshheading:19844814-Genotype,
pubmed-meshheading:19844814-Humans,
pubmed-meshheading:19844814-Polycystic Ovary Syndrome,
pubmed-meshheading:19844814-Polymorphism, Single Nucleotide,
pubmed-meshheading:19844814-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
FABP4: a novel candidate gene for polycystic ovary syndrome.
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pubmed:affiliation |
Reproductive Medicine Center, The First Affiliated Hospital, Anhui Medical University, Hefei, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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