Source:http://linkedlifedata.com/resource/pubmed/id/19800439
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
52
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pubmed:dateCreated |
2009-12-1
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pubmed:abstractText |
The present study describes the effects of a commercially available genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) on clinical, pathological and virological features in three multi-site farms suffering from postweaning multisystemic wasting syndrome (PMWS). The vaccine product was able to reduce clinical signs, PCV2 viral load in lymphoid organs and/or sera, and overall mortality in nurseries and fattening units. This is the first time in which is shown that a PCV2 vaccine is able to decrease specifically PMWS-associated mortality. Another novelty of this study is the assessment of PMWS-like histological lesions in a large number of vaccinated and non-vaccinated pigs under field conditions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1873-2518
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pubmed:author |
pubmed-author:AlegreAA,
pubmed-author:BalaschMM,
pubmed-author:BruTT,
pubmed-author:ChuH-JHJ,
pubmed-author:CrisciEE,
pubmed-author:FraileLL,
pubmed-author:López-SoriaSS,
pubmed-author:NofraríasMM,
pubmed-author:Plana-DuranJJ,
pubmed-author:SegalésJJ,
pubmed-author:SibilaMM,
pubmed-author:UrnizaAA,
pubmed-author:XuZZ
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pubmed:issnType |
Electronic
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pubmed:day |
9
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7313-21
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pubmed:meshHeading |
pubmed-meshheading:19800439-Animals,
pubmed-meshheading:19800439-Antibodies, Viral,
pubmed-meshheading:19800439-Circoviridae Infections,
pubmed-meshheading:19800439-DNA, Viral,
pubmed-meshheading:19800439-Female,
pubmed-meshheading:19800439-Genetic Engineering,
pubmed-meshheading:19800439-Male,
pubmed-meshheading:19800439-Porcine Postweaning Multisystemic Wasting Syndrome,
pubmed-meshheading:19800439-Swine,
pubmed-meshheading:19800439-Viral Load,
pubmed-meshheading:19800439-Viral Vaccines
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pubmed:year |
2009
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pubmed:articleTitle |
A genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) improves clinical, pathological and virological outcomes in postweaning multisystemic wasting syndrome affected farms.
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pubmed:affiliation |
Centre de Recerca en Sanitat Animal, UAB-IRTA, Campus de la Universitat, Autònoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. joaquim.segales@uab.cat
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pubmed:publicationType |
Journal Article
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