Linked Life Data

19789

Source:http://linkedlifedata.com/resource/pubmed/id/19789

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
961
pubmed:dateCreated
1977-10-20
pubmed:abstractText
In this paper, we shall show that there are substantial numbers of nerve terminals which are normally ineffective. In the intact animal, occasional signs of the postsynaptic effectiveness of these fibres can be seen under conditions of optimal spatial summation or increased excitability or decreased inhibition. If the normally functioning afferent nerve fibres are blocked or cut, some of the previously ineffective fibres immediately establish an effective drive of cells. If the normal afferents are cut and allowed to degenerate, large numbers of cells begin to respond to new inputs. The presence of ineffective synapses in the adult offers an alternative to sprouting or the opening up of polysynaptic pathways as a possible mechanism to explain plasticity of connections in adult brains.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0962-8436
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
278
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
361-72
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
The presence of ineffective synapses and the circumstances which unmask them.
pubmed:publicationType
Journal Article