Linked Life Data

19780715

Source:http://linkedlifedata.com/resource/pubmed/id/19780715

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-9-28
pubmed:abstractText
The current epidemic of obesity has caused a surge of interest in the study of the mechanisms regulating adipose tissue formation. It has been observed that adipose tissue contains a pool of adult stem cells with multipotent properties, which provide for the physiological cell turnover, and can be isolated and potentially utilized for tissue engineering and regenerative medical applications. These "stromal" cells exhibit pre-adipocyte characteristics, can be isolated from adipose tissue of adult subjects, propagated in vitro, and induced to differentiate into adipocytes. Different populations of multi-potent precursor cells can be isolated from human fat fragments. Thus, adipose precursors cells are a heterogeneous cells population, consisting of fibroblast-like multi-potential stem cells generally termed adipose-derived stem cells (ASCs). In this review, we discuss some aspects of ASCs basic biology, the methodology involved in ASCs isolation and culture, and some implications of ASCs availability for the understanding of metabolic diseases in humans.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1744-4160
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
218-26
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Human adipose tissue precursor cells: a new factor linking regulation of fat mass to obesity and type 2 diabetes?
pubmed:affiliation
Department of Emergency and Organ Transplantation, Section of Internal Medicine, Endocrinology, Andrology and Metabolic Diseases, University of Bari School of Medicine, Bari, Italy.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't