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| pubmed-article:19761585 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:19761585 | lifeskim:mentions | umls-concept:C1413560 | lld:lifeskim |
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| pubmed-article:19761585 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:19761585 | pubmed:dateCreated | 2009-9-30 | lld:pubmed |
| pubmed-article:19761585 | pubmed:abstractText | Human T-cell leukemia virus type 1 (HTLV-1) is a causative agent of adult T-cell leukemia (ATL), whereas its relative HTLV-2 is not associated with any malignancies including ATL. HTLV-1 Tax1 transformed a T-cell line from interleukin (IL)-2-dependent growth to IL-2-independent growth, with an activity that was much more potent in comparison to HTLV-2 Tax2. This distinction was mediated by at least two Tax1 specific functions, an interaction with host cellular factors through the PDZ domain binding motif (PBM) and the activation of NF-kappa B2 (NF-kappa B2)/p100. | lld:pubmed |
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| pubmed-article:19761585 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:19761585 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:19761585 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19761585 | pubmed:issn | 1742-4690 | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:TakahashiMasa... | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:HiguchiMasaya... | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:TanakaYuetsuY | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:AoyagiYutakaY | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:OieMasayasuM | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:FujiiMasahiro... | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:KondoRieR | lld:pubmed |
| pubmed-article:19761585 | pubmed:author | pubmed-author:ShojiToshiyuk... | lld:pubmed |
| pubmed-article:19761585 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19761585 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:19761585 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19761585 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19761585 | pubmed:pagination | 83 | lld:pubmed |
| pubmed-article:19761585 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:19761585 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19761585 | pubmed:articleTitle | Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2. | lld:pubmed |
| pubmed-article:19761585 | pubmed:affiliation | Division of Virology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-Dori, Niigata 951-8510, Japan. shoji-t@med.niigata-u.ac.jp | lld:pubmed |
| pubmed-article:19761585 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19761585 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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