Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-9-29
pubmed:abstractText
Myocardial infarction results as a consequence of atherosclerotic plaque rupture, with plaque stability largely depending on the lesion forming extracellular matrix components. Lipid enriched non-calcified lesions are considered more instable and rupture prone than calcified lesions. Matrix metalloproteinases (MMPs) are extracellular matrix degrading enzymes with plaque destabilisating characteristics which have been implicated in atherogenesis. We therefore hypothesised MMP-1 and MMP-9 serum levels to be associated with non-calcified lesions as determined by CT-angiography in patients with coronary artery disease.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-10199873, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-10330380, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-10636267, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-11222465, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-12633805, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-12668489, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-12730128, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-14675588, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-14691045, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-15063437, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-15191780, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-15981119, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16054454, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16127182, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16210545, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16631006, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16843181, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-17007239, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-17268019, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-17990073, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18073479, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18197181, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18617071, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18663625, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18676684, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18772495, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18823886, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-19229071, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-19266101, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-7648691, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-7759694, http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-9403605
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1475-2840
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
50
pubmed:meshHeading
pubmed-meshheading:19751510-Adipose Tissue, pubmed-meshheading:19751510-Adrenergic beta-Antagonists, pubmed-meshheading:19751510-Aged, pubmed-meshheading:19751510-Biological Markers, pubmed-meshheading:19751510-Body Mass Index, pubmed-meshheading:19751510-Calcinosis, pubmed-meshheading:19751510-Chest Pain, pubmed-meshheading:19751510-Cholesterol, pubmed-meshheading:19751510-Coronary Angiography, pubmed-meshheading:19751510-Coronary Artery Disease, pubmed-meshheading:19751510-Coronary Stenosis, pubmed-meshheading:19751510-Female, pubmed-meshheading:19751510-Humans, pubmed-meshheading:19751510-Male, pubmed-meshheading:19751510-Matrix Metalloproteinase 1, pubmed-meshheading:19751510-Matrix Metalloproteinase 9, pubmed-meshheading:19751510-Middle Aged, pubmed-meshheading:19751510-Pericardium, pubmed-meshheading:19751510-Predictive Value of Tests, pubmed-meshheading:19751510-Risk Factors, pubmed-meshheading:19751510-Tomography, Spiral Computed, pubmed-meshheading:19751510-Triglycerides
pubmed:year
2009
pubmed:articleTitle
MMP-1 serum levels predict coronary atherosclerosis in humans.
pubmed:affiliation
Department of Internal Medicine II, University of Munich, Munich, Germany. Michael.Lehrke@med.uni-muenchen.de
pubmed:publicationType
Journal Article, Comparative Study