rdf:type |
|
lifeskim:mentions |
|
pubmed:dateCreated |
2009-9-29
|
pubmed:abstractText |
Myocardial infarction results as a consequence of atherosclerotic plaque rupture, with plaque stability largely depending on the lesion forming extracellular matrix components. Lipid enriched non-calcified lesions are considered more instable and rupture prone than calcified lesions. Matrix metalloproteinases (MMPs) are extracellular matrix degrading enzymes with plaque destabilisating characteristics which have been implicated in atherogenesis. We therefore hypothesised MMP-1 and MMP-9 serum levels to be associated with non-calcified lesions as determined by CT-angiography in patients with coronary artery disease.
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-10199873,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-10330380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-10636267,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-11222465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-12633805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-12668489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-12730128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-14675588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-14691045,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-15063437,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-15191780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-15981119,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16054454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16127182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16210545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16631006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-16843181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-17007239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-17268019,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-17990073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18073479,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18197181,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18617071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18663625,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18676684,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18772495,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-18823886,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-19229071,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-19266101,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-7648691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-7759694,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19751510-9403605
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1475-2840
|
pubmed:author |
pubmed-author:BeckerAlexanderA,
pubmed-author:BeckerChristophC,
pubmed-author:BroedlUli CUC,
pubmed-author:GökeBurkhardB,
pubmed-author:GreifMartinM,
pubmed-author:LaubenderRüdiger PRP,
pubmed-author:LeberAlexander WAW,
pubmed-author:LebherzCorinnaC,
pubmed-author:LehrkeMichaelM,
pubmed-author:ParhoferKlaus GKG,
pubmed-author:ReiserMaximilianM,
pubmed-author:SteinbeckGerhardG,
pubmed-author:TittusJanineJ,
pubmed-author:von ZieglerFranzF
|
pubmed:issnType |
Electronic
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
50
|
pubmed:meshHeading |
pubmed-meshheading:19751510-Adipose Tissue,
pubmed-meshheading:19751510-Adrenergic beta-Antagonists,
pubmed-meshheading:19751510-Aged,
pubmed-meshheading:19751510-Biological Markers,
pubmed-meshheading:19751510-Body Mass Index,
pubmed-meshheading:19751510-Calcinosis,
pubmed-meshheading:19751510-Chest Pain,
pubmed-meshheading:19751510-Cholesterol,
pubmed-meshheading:19751510-Coronary Angiography,
pubmed-meshheading:19751510-Coronary Artery Disease,
pubmed-meshheading:19751510-Coronary Stenosis,
pubmed-meshheading:19751510-Female,
pubmed-meshheading:19751510-Humans,
pubmed-meshheading:19751510-Male,
pubmed-meshheading:19751510-Matrix Metalloproteinase 1,
pubmed-meshheading:19751510-Matrix Metalloproteinase 9,
pubmed-meshheading:19751510-Middle Aged,
pubmed-meshheading:19751510-Pericardium,
pubmed-meshheading:19751510-Predictive Value of Tests,
pubmed-meshheading:19751510-Risk Factors,
pubmed-meshheading:19751510-Tomography, Spiral Computed,
pubmed-meshheading:19751510-Triglycerides
|
pubmed:year |
2009
|
pubmed:articleTitle |
MMP-1 serum levels predict coronary atherosclerosis in humans.
|
pubmed:affiliation |
Department of Internal Medicine II, University of Munich, Munich, Germany. Michael.Lehrke@med.uni-muenchen.de
|
pubmed:publicationType |
Journal Article,
Comparative Study
|