| pubmed-article:1971863 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1971863 | lifeskim:mentions | umls-concept:C0166049 | lld:lifeskim |
| pubmed-article:1971863 | lifeskim:mentions | umls-concept:C0019069 | lld:lifeskim |
| pubmed-article:1971863 | lifeskim:mentions | umls-concept:C0341439 | lld:lifeskim |
| pubmed-article:1971863 | pubmed:issue | 8698 | lld:pubmed |
| pubmed-article:1971863 | pubmed:dateCreated | 1990-7-9 | lld:pubmed |
| pubmed-article:1971863 | pubmed:abstractText | A radioimmunoassay was used to detect antibodies to hepatitis C virus (anti-HCV) in 154 patients with haemophilia. Prevalence of anti-HCV was associated with exposure to clotting factor concentrates. 76 of 129 (59%) who had received factor VIII or IX had anti-HCV: 42 of 55 (76%) who required over 10,000 units of concentrate annually had anti-HCV, compared with 34 of 74 (46%) who required less, and 0 of 25 patients who had never received concentrates. Anti-HCV were significantly more common in patients seropositive for antibodies against human immunodeficiency virus (anti-HIV) or with markers of previous hepatitis B infection than in those without anti-HIV or hepatitis B markers (88% vs 39% and 75% vs 46%, respectively). 5 of 23 (22%) haemophiliacs treated only with heated concentrates had anti-HCV compared with 71 of 106 (67%) patients who received unmodified products. 35 patients with chronic liver disease underwent liver biopsy: histological examination showed features associated with post-transfusion hepatitis in 24, all of whom were anti-HCV-positive; of the other 11 patients with no histological features of non-A, non-B hepatitis, 5 were anti-HCV-positive. HCV appears to be the major predisposing factor for most non-A, non-B hepatitis and chronic liver disease in haemophilia. | lld:pubmed |
| pubmed-article:1971863 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971863 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971863 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1971863 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1971863 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:1971863 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1971863 | pubmed:month | May | lld:pubmed |
| pubmed-article:1971863 | pubmed:issn | 0140-6736 | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:UnderwoodJ... | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:PrestonF EFE | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:TrigerD RDR | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:KutHH | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:HoughtonMM | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:ChooQ LQL | lld:pubmed |
| pubmed-article:1971863 | pubmed:author | pubmed-author:MakrisMM | lld:pubmed |
| pubmed-article:1971863 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1971863 | pubmed:day | 12 | lld:pubmed |
| pubmed-article:1971863 | pubmed:volume | 335 | lld:pubmed |
| pubmed-article:1971863 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1971863 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1971863 | pubmed:pagination | 1117-9 | lld:pubmed |
| pubmed-article:1971863 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:1971863 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1971863 | pubmed:articleTitle | Hepatitis C antibody and chronic liver disease in haemophilia. | lld:pubmed |
| pubmed-article:1971863 | pubmed:affiliation | Department of Haematology, Royal Hallamshire Hospital, Sheffield, UK. | lld:pubmed |
| pubmed-article:1971863 | pubmed:publicationType | Journal Article | lld:pubmed |
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