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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8702
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pubmed:dateCreated |
1990-7-5
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pubmed:abstractText |
Untreated urine specimens from 358 patients (344 attending genito-urinary medicine clinics, 14 haemophiliacs) and 353 blood donors were tested blind by a simple IgG-capture particle-adherence test (GACPAT) and a rapid IgG-capture enzyme-linked immunosorbent assay (GACELISA) for antibody to human immunodeficiency virus (anti-HIV). All 158 urine specimens from seropositive subjects were anti-HIV positive by GACPAT and 157 of them (99.4%) were positive by GACELISA. Tests on 553 urine specimens from seronegative subjects gave two repeatable false-positive reactions by GACPAT (0.4%) and none by GACELISA. By means of a modified procedure anti-gp160 was detected by commercial western blot in the urine of 44 of 45 seropositive subjects examined. IgG-capture assays will detect anti-HIV in unconcentrated urine and so allow a diagnosis in circumstances when blood sampling is impracticable.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0140-6736
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
335
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1366-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1971662-Blotting, Western,
pubmed-meshheading:1971662-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1971662-False Positive Reactions,
pubmed-meshheading:1971662-HIV Antibodies,
pubmed-meshheading:1971662-Humans,
pubmed-meshheading:1971662-Immune Adherence Reaction,
pubmed-meshheading:1971662-Immunoglobulin G,
pubmed-meshheading:1971662-Immunologic Techniques,
pubmed-meshheading:1971662-Sensitivity and Specificity
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pubmed:year |
1990
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pubmed:articleTitle |
Preliminary report: accurate assays for anti-HIV in urine.
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pubmed:affiliation |
PHLS Virus Reference Laboratory, London, UK.
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pubmed:publicationType |
Journal Article
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