19713999

Source:http://linkedlifedata.com/resource/pubmed/id/19713999

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0031809, umls-concept:C0205210, umls-concept:C1099354, umls-concept:C1280500, umls-concept:C1521840, umls-concept:C1527148, umls-concept:C2930586
pubmed:issue	11
pubmed:dateCreated	2009-10-16
pubmed:abstractText	This review considers comparisons of the off-target effects of siRNA to shRNA and their potential impact on the efficacy and toxicity of RNAi based therapeutics.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9432230
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/MicroRNAs, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	1476-5500
pubmed:author	pubmed-author:ClearyM AMA, pubmed-author:NemunaitisJJ, pubmed-author:RaoD DDD, pubmed-author:SenzerNN
pubmed:issnType	Electronic
pubmed:volume	16
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	807-9
pubmed:meshHeading	pubmed-meshheading:19713999-Gene Therapy, pubmed-meshheading:19713999-Humans, pubmed-meshheading:19713999-MicroRNAs, pubmed-meshheading:19713999-Neoplasms, pubmed-meshheading:19713999-RNA, Small Interfering, pubmed-meshheading:19713999-RNA Interference
pubmed:year	2009
pubmed:articleTitle	Comparative assessment of siRNA and shRNA off target effects: what is slowing clinical development.
pubmed:affiliation	Gradalis Inc., Dallas, TX, USA.
pubmed:publicationType	Journal Article, Review