19713226

Source:http://linkedlifedata.com/resource/pubmed/id/19713226

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0205210, umls-concept:C0220901, umls-concept:C0751606, umls-concept:C2348519
pubmed:issue	2
pubmed:dateCreated	2010-2-8
pubmed:abstractText	The t(9;22) and t(4;11) chromosomal translocations, which generate the BCR-ABL and MLL-AF4 fusion genes, define high-risk subtypes of acute lymphoblastic leukemia in adults. However, the prognostic impact of other rarer fusion genes is less well established in adult acute lymphoblastic leukemia than in the childhood form.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0417435
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Fusion Proteins, bcr-abl, http://linkedlifedata.com/resource/pubmed/chemical/MLL-AF4 fusion protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Myeloid-Lymphoid Leukemia Protein, http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Proteins, Fusion, http://linkedlifedata.com/resource/pubmed/chemical/TCF3-PBX1 fusion protein, human, http://linkedlifedata.com/resource/pubmed/chemical/abl-bcr fusion protein, human
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	1592-8721
pubmed:author	pubmed-author:BurmeisterThomasT, pubmed-author:FischerLarsL, pubmed-author:GökbugetNicolaN, pubmed-author:HoelzerDieterD, pubmed-author:HubertDanielaD, pubmed-author:SchwartzStefanS, pubmed-author:SindramAnnetteA, pubmed-author:ThielEckhardE
pubmed:issnType	Electronic
pubmed:volume	95
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	241-6
pubmed:dateRevised	2010-9-27
pubmed:meshHeading	pubmed-meshheading:19713226-Adolescent, pubmed-meshheading:19713226-Adult, pubmed-meshheading:19713226-Cell Line, pubmed-meshheading:19713226-Female, pubmed-meshheading:19713226-Fusion Proteins, bcr-abl, pubmed-meshheading:19713226-Humans, pubmed-meshheading:19713226-Male, pubmed-meshheading:19713226-Middle Aged, pubmed-meshheading:19713226-Myeloid-Lymphoid Leukemia Protein, pubmed-meshheading:19713226-Oncogene Proteins, Fusion, pubmed-meshheading:19713226-Precursor Cell Lymphoblastic Leukemia-Lymphoma, pubmed-meshheading:19713226-Prognosis, pubmed-meshheading:19713226-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:19713226-Young Adult
pubmed:year	2010
pubmed:articleTitle	Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia.
pubmed:affiliation	Med Klinik für Hämatologie/Onkologie Hindenburgdamm 30, 12200 Berlin, Germany. thomas.burmeister@charite.de
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't