Source:http://linkedlifedata.com/resource/pubmed/id/19713173
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2009-8-28
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| pubmed:abstractText |
The objective of this study is to evaluate the long-term clinical significance of enteral nutrition (EN) in weaning adult short bowel patients off parenteral nutrition (PN) undergoing intestinal rehabilitation therapy (IRT). Sixty-one adult patients with small bowel length 47.95+/-19.37 cm were retrospectively analyzed. After a 3-week IRT program, including recombinant human growth hormone (rhGH, 0.05 mg/kg/d), glutamine (30 g/d), and combined EN and PN support, patients were maintained on EN or plus a high-carbohydrate, low fat (HCLF) diet. Continuous tube feeding was used when EN was started. Patients were followed up for 50.34+/-24.38 months and had an overall survival rate 95.08% (58/61). On last evaluation, 85.24% (52/61) of the patients were free of PN. For 77.42% patients (24/31) with small bowel length<35 cm in jejunoileocolic anastomosis (type III) and <60 cm in jejunocolic anastomosis (type II), weaning off PN was achieved. EN comprised of 52.56+/-13.47% of patients' daily calorie requirements on follow-up. Five patients were maintained on home PN (HPN) plus EN. Nutritional and anthropometric parameters, urine 5-hr D-xylose excretion and serum citrulline levels all increased significantly after IRT and on follow-up compared with baseline. In conclusion, with proper EN management during and after IRT, a significant number of SBS patients could be weaned from PN, especially for those who were considered as permanent intestinal failure; continuous tube feeding is recommended for enteral access, and long-term EN support could meet the daily nutritional requirement in majority of SBS patients.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
0964-7058
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
18
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
155-63
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| pubmed:meshHeading |
pubmed-meshheading:19713173-Adolescent,
pubmed-meshheading:19713173-Adult,
pubmed-meshheading:19713173-Aged,
pubmed-meshheading:19713173-Body Mass Index,
pubmed-meshheading:19713173-Body Weight,
pubmed-meshheading:19713173-Enteral Nutrition,
pubmed-meshheading:19713173-Female,
pubmed-meshheading:19713173-Human Growth Hormone,
pubmed-meshheading:19713173-Humans,
pubmed-meshheading:19713173-Male,
pubmed-meshheading:19713173-Middle Aged,
pubmed-meshheading:19713173-Nutritional Requirements,
pubmed-meshheading:19713173-Parenteral Nutrition,
pubmed-meshheading:19713173-Parenteral Nutrition, Home,
pubmed-meshheading:19713173-Recombinant Proteins,
pubmed-meshheading:19713173-Retrospective Studies,
pubmed-meshheading:19713173-Short Bowel Syndrome,
pubmed-meshheading:19713173-Treatment Outcome
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| pubmed:year |
2009
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| pubmed:articleTitle |
Role of enteral nutrition in adult short bowel syndrome undergoing intestinal rehabilitation: the long-term outcome.
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| pubmed:affiliation |
Research Institute of General Surgery, Jinling Hospital, Nanjing, 210002, PR China.
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| pubmed:publicationType |
Journal Article
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