Source:http://linkedlifedata.com/resource/pubmed/id/19705056
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2010-1-29
|
| pubmed:abstractText |
Only some carriers of human T cell lymphotropic virus type I (HTLV-1) develop adult T cell leukemia/lymphoma (ATLL) after a long latency period, and an association has been reported between chronic refractory eczema, known as infective dermatitis, and young-onset ATLL. A 25-year-old female developed ATLL and underwent allogeneic hematopoietic stem cell transplantation (HSCT) in non-remission. She had chronic refractory eczema and corneal injury at the onset of ATLL. Remission of ATLL was achieved, and the HTLV-1 proviral load decreased after HSCT. In addition, her pre-existing eczema and corneal injuries almost disappeared. More than a year has passed since the transplantation was performed, and she has had no recurrence of either ATLL or lesions in the skin and eye. Her clinical course suggests a possible association between skin and eye lesions and HTLV-1 infection. Changes in the immunological condition after HSCT might play a key role. Special attention is needed when HTLV-1 carriers develop eye or skin lesions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
1865-3774
|
| pubmed:author |
pubmed-author:AokiSatokoS,
pubmed-author:DemitsuToshioT,
pubmed-author:HiguchiTakakazuT,
pubmed-author:KakehashiAkihiroA,
pubmed-author:KakoShinichiS,
pubmed-author:KandaYoshinobuY,
pubmed-author:KimuraShun-IchiS,
pubmed-author:MiyamuraFumiyaF,
pubmed-author:NöllG NGN,
pubmed-author:NakasoneHidekiH,
pubmed-author:NishidaJunjiJ,
pubmed-author:OkudaShinyaS,
pubmed-author:OshimaKumiK,
pubmed-author:SatoMikiM,
pubmed-author:TerasakoKirikoK,
pubmed-author:YamagamiHirokoH,
pubmed-author:YamazakiRieR,
pubmed-author:YoshinagaKentaroK
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
90
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
397-401
|
| pubmed:meshHeading |
pubmed-meshheading:19705056-Adult,
pubmed-meshheading:19705056-Chronic Disease,
pubmed-meshheading:19705056-Corneal Diseases,
pubmed-meshheading:19705056-Eczema,
pubmed-meshheading:19705056-Female,
pubmed-meshheading:19705056-HTLV-I Infections,
pubmed-meshheading:19705056-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:19705056-Human T-lymphotropic virus 1,
pubmed-meshheading:19705056-Humans,
pubmed-meshheading:19705056-Leukemia-Lymphoma, Adult T-Cell,
pubmed-meshheading:19705056-Transplantation, Homologous,
pubmed-meshheading:19705056-Treatment Outcome,
pubmed-meshheading:19705056-Viral Load
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Successful treatment of young-onset adult T cell leukemia/lymphoma and preceding chronic refractory eczema and corneal injury by allogeneic hematopoietic stem cell transplantation.
|
| pubmed:affiliation |
Division of Hematology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-ku, Saitama, Saitama, 330-8503, Japan.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|