| pubmed-article:1969877 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1969877 | lifeskim:mentions | umls-concept:C0020971 | lld:lifeskim |
| pubmed-article:1969877 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
| pubmed-article:1969877 | lifeskim:mentions | umls-concept:C0020846 | lld:lifeskim |
| pubmed-article:1969877 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:1969877 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:1969877 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:1969877 | pubmed:dateCreated | 1990-5-17 | lld:pubmed |
| pubmed-article:1969877 | pubmed:abstractText | IL-4 induces Thy-1 expression and IgE secretion by LPS--and T cell-stimulated murine B cells in vitro. IFN-gamma inhibits both of these IL-4-mediated effects. IL-4 and IFN-gamma are often exclusively produced by different CD4+ T cell subsets. Injection of mice with a polyclonal goat anti-mouse IgD antibody (GaM delta) stimulates large increases in the serum concentration of IgE through the production of IL-4. Neutralization of endogenous IFN-gamma production in GaM delta-injected mice leads to further increases in serum IgE levels. We show that IL-4 and IFN-gamma, produced after GaM delta injection, respectively, stimulate and inhibit the number of splenic B cells expressing Thy-1 in vivo. Increased numbers of Thy-1-expressing B cells are observed concomitantly with the onset of enhanced IgE secretion. These Thy-1-expressing B cells are highly and selectively enriched for IgE-secreting cells. | lld:pubmed |
| pubmed-article:1969877 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1969877 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1969877 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1969877 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1969877 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:1969877 | pubmed:author | pubmed-author:FinkelmanF... | lld:pubmed |
| pubmed-article:1969877 | pubmed:author | pubmed-author:BarbieriSS | lld:pubmed |
| pubmed-article:1969877 | pubmed:author | pubmed-author:SnapperC MCM | lld:pubmed |
| pubmed-article:1969877 | pubmed:author | pubmed-author:HooleyJ JJJ | lld:pubmed |
| pubmed-article:1969877 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1969877 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:1969877 | pubmed:volume | 144 | lld:pubmed |
| pubmed-article:1969877 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1969877 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1969877 | pubmed:pagination | 2940-5 | lld:pubmed |
| pubmed-article:1969877 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:1969877 | pubmed:meshHeading | pubmed-meshheading:1969877-... | lld:pubmed |
| pubmed-article:1969877 | pubmed:meshHeading | pubmed-meshheading:1969877-... | lld:pubmed |
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| pubmed-article:1969877 | pubmed:meshHeading | pubmed-meshheading:1969877-... | lld:pubmed |
| pubmed-article:1969877 | pubmed:meshHeading | pubmed-meshheading:1969877-... | lld:pubmed |
| pubmed-article:1969877 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:1969877 | pubmed:articleTitle | Murine B cells expressing Thy-1 after in vivo immunization selectively secrete IgE. | lld:pubmed |
| pubmed-article:1969877 | pubmed:affiliation | Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814. | lld:pubmed |
| pubmed-article:1969877 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1969877 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1969877 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
