rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
2009-8-26
|
pubmed:abstractText |
Biotransformation of dihydroresveratrol by crude Momordica charantia peroxidase provided six new acyclic bis[bibenzyls] 1-6. Their structures were established on the basis of NMR and MS analyses as C-C, C-O-C, and C-CH(2)-C dimers of dihydroresveratrol. Compounds 1-6 were tested for antiproliferative activity against human prostate cancer PC3 cell line in vitro, and 2 and 6 were found to be more potent than the parent compound.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
1612-1880
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
6
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1193-201
|
pubmed:meshHeading |
pubmed-meshheading:19697337-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:19697337-Bibenzyls,
pubmed-meshheading:19697337-Biocatalysis,
pubmed-meshheading:19697337-Biotransformation,
pubmed-meshheading:19697337-Cell Line, Tumor,
pubmed-meshheading:19697337-Chromatography, High Pressure Liquid,
pubmed-meshheading:19697337-Dimerization,
pubmed-meshheading:19697337-Humans,
pubmed-meshheading:19697337-Male,
pubmed-meshheading:19697337-Momordica charantia,
pubmed-meshheading:19697337-Peroxidases,
pubmed-meshheading:19697337-Prostatic Neoplasms,
pubmed-meshheading:19697337-Spectrometry, Mass, Electrospray Ionization,
pubmed-meshheading:19697337-Stilbenes
|
pubmed:year |
2009
|
pubmed:articleTitle |
Biocatalytic production of acyclic bis[bibenzyls] from dihydroresveratrol by crude Momordica charantia peroxidase.
|
pubmed:affiliation |
School of Pharmaceutical Sciences, Shandong University, Jinan, PR China.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|