19690618

Source:http://linkedlifedata.com/resource/pubmed/id/19690618

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008059, umls-concept:C0024535, umls-concept:C0027567, umls-concept:C0034656, umls-concept:C0205653, umls-concept:C0282461, umls-concept:C0936150
pubmed:issue	8
pubmed:dateCreated	2009-8-19
pubmed:databankReference	http://linkedlifedata.com/resource/pubmed/xref/ClinicalTrials.gov/NCT00344006
pubmed:abstractText	Chlorproguanil-dapsone-artesunate (CDA) was developed as an affordable, simple, fixed-dose artemisinin-based combination therapy for use in Africa. This trial was a randomized parallel-group, double-blind, double-dummy study to compare CDA and artemether-lumefantrine (AL) efficacy in uncomplicated Plasmodium falciparum malaria and further define the CDA safety profile, particularly its hematological safety in glucose-6-phosphate dehydrogenase (G6PD) -deficient patients.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101285081
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials, http://linkedlifedata.com/resource/pubmed/chemical/Artemisinins, http://linkedlifedata.com/resource/pubmed/chemical/Dapsone, http://linkedlifedata.com/resource/pubmed/chemical/Ethanolamines, http://linkedlifedata.com/resource/pubmed/chemical/Fluorenes, http://linkedlifedata.com/resource/pubmed/chemical/Proguanil, http://linkedlifedata.com/resource/pubmed/chemical/artesunate, http://linkedlifedata.com/resource/pubmed/chemical/chlorproguanil, http://linkedlifedata.com/resource/pubmed/chemical/lumefantrine
pubmed:status	MEDLINE
pubmed:issn	1932-6203
pubmed:author	pubmed-author:BorrmannSteffenS, pubmed-author:DuparcStephanS, pubmed-author:EsamaiFabianF, pubmed-author:EzedinachiEmmanuel UEU, pubmed-author:GreenwoodBrianB, pubmed-author:GuiguemdéRobertR, pubmed-author:KellamLyndaL, pubmed-author:KirbyPaula LPL, pubmed-author:OgucheStephenS, pubmed-author:Owusu-AgyeiSethS, pubmed-author:PambaAllanA, pubmed-author:PremjiZulZ, pubmed-author:SowunmiAkintundeA, pubmed-author:UmehRich ERE, pubmed-author:WardStephen ASA, pubmed-author:WinstanleyPeter APA
pubmed:issnType	Electronic
pubmed:volume	4
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e6682
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:19690618-Adolescent, pubmed-meshheading:19690618-Africa, pubmed-meshheading:19690618-Antimalarials, pubmed-meshheading:19690618-Artemisinins, pubmed-meshheading:19690618-Child, pubmed-meshheading:19690618-Dapsone, pubmed-meshheading:19690618-Double-Blind Method, pubmed-meshheading:19690618-Ethanolamines, pubmed-meshheading:19690618-Female, pubmed-meshheading:19690618-Fluorenes, pubmed-meshheading:19690618-Humans, pubmed-meshheading:19690618-Malaria, Falciparum, pubmed-meshheading:19690618-Male, pubmed-meshheading:19690618-Patient Compliance, pubmed-meshheading:19690618-Proguanil, pubmed-meshheading:19690618-Treatment Outcome
pubmed:year	2009
pubmed:articleTitle	Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria.
pubmed:affiliation	Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. zpremji@muhas.ac.tz
pubmed:publicationType	Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study

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