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rdf:type |
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lifeskim:mentions |
umls-concept:C0020792,
umls-concept:C0030705,
umls-concept:C0085862,
umls-concept:C0332597,
umls-concept:C0750901,
umls-concept:C1299583,
umls-concept:C1364818,
umls-concept:C1533134,
umls-concept:C1549571,
umls-concept:C1556094,
umls-concept:C1608386,
umls-concept:C1708726
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pubmed:issue |
9
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pubmed:dateCreated |
2009-8-17
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pubmed:abstractText |
The occurrence of duplications of the amyloid precursor protein gene (APP) has been described in European families with early-onset familial Alzheimer disease (EO-FAD) and cerebral amyloid angiopathy. However, the contribution of APP duplication to the development of AD in other ethnic populations remains undetermined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1468-330X
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pubmed:author |
pubmed-author:IkeuchiTT,
pubmed-author:KasugaKK,
pubmed-author:KuwanoRR,
pubmed-author:MatsumotoNN,
pubmed-author:MiyashitaAA,
pubmed-author:MizuguchiTT,
pubmed-author:NishimuraAA,
pubmed-author:NishizawaMM,
pubmed-author:OhnoTT,
pubmed-author:OnoderaOO,
pubmed-author:ShigiYY,
pubmed-author:ShimohataTT,
pubmed-author:TokunagaJJ
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pubmed:issnType |
Electronic
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1050-2
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pubmed:meshHeading |
pubmed-meshheading:19684239-Age of Onset,
pubmed-meshheading:19684239-Alzheimer Disease,
pubmed-meshheading:19684239-Amyloid beta-Protein Precursor,
pubmed-meshheading:19684239-Apolipoproteins E,
pubmed-meshheading:19684239-Atrophy,
pubmed-meshheading:19684239-Brain,
pubmed-meshheading:19684239-Cohort Studies,
pubmed-meshheading:19684239-DNA,
pubmed-meshheading:19684239-Female,
pubmed-meshheading:19684239-Gene Dosage,
pubmed-meshheading:19684239-Gene Duplication,
pubmed-meshheading:19684239-Humans,
pubmed-meshheading:19684239-Japan,
pubmed-meshheading:19684239-Magnetic Resonance Imaging,
pubmed-meshheading:19684239-Male,
pubmed-meshheading:19684239-Middle Aged,
pubmed-meshheading:19684239-Neuropsychological Tests,
pubmed-meshheading:19684239-Pedigree,
pubmed-meshheading:19684239-RNA, Messenger,
pubmed-meshheading:19684239-tau Proteins
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pubmed:year |
2009
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pubmed:articleTitle |
Identification of independent APP locus duplication in Japanese patients with early-onset Alzheimer disease.
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pubmed:affiliation |
Department of Molecular Neuroscience, Bioresource Science Branch, Center for Bioresources, Brain Research Institute, Niigata University, Niigata, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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