Source:http://linkedlifedata.com/resource/pubmed/id/19683993
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
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| pubmed:dateCreated |
2009-8-17
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| pubmed:abstractText |
Cerebral damage is a major problem after reconstructive surgery of the aortic arch and the descending aorta. Current protective strategies, including deep hypothermia and antegrade cerebral perfusion (ACP), are used to prolong the tolerated duration of circulatory arrest. The aim of the study was to observe the influence of deep hypothermic circulatory arrest (DHCA) and ACP on neuronal apoptosis in the hippocampus. To further elucidate the mechanisms of neurologic injury and protection, we assessed the expression of the antiapoptotic protein Bcl-2 and the proapoptotic protein Bax.
|
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
1522-6662
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
12
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
E219-24
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| pubmed:meshHeading |
pubmed-meshheading:19683993-Animals,
pubmed-meshheading:19683993-Apoptosis,
pubmed-meshheading:19683993-Brain Injuries,
pubmed-meshheading:19683993-Circulatory Arrest, Deep Hypothermia Induced,
pubmed-meshheading:19683993-Hippocampus,
pubmed-meshheading:19683993-Male,
pubmed-meshheading:19683993-Neurons,
pubmed-meshheading:19683993-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:19683993-Reperfusion,
pubmed-meshheading:19683993-Swine
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| pubmed:year |
2009
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| pubmed:articleTitle |
Antegrade cerebral perfusion during deep hypothermia circulatory arrest attenuates the apoptosis of neurons in porcine hippocampus.
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| pubmed:affiliation |
Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
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| pubmed:publicationType |
Journal Article
|