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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2009-9-17
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pubmed:abstractText |
Insulin resistance induces increased pulse pressure (PP), endothelial dysfunction (ED), and reduced bioavailability of endothelium-derived nitric oxide (NO). The genetic background of these 3 cardiovascular risk factors might be partly common. The ENPP1 K121Q polymorphism is associated with insulin resistance and cardiovascular risk.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:BacciSimonettaS,
pubmed-author:BarattaRobertoR,
pubmed-author:ConsoliAgostinoA,
pubmed-author:Di FulvioPatriziaP,
pubmed-author:Di PaolaRosaR,
pubmed-author:Di SilvestreSaraS,
pubmed-author:FiniGraziaG,
pubmed-author:FormosoGloriaG,
pubmed-author:FrittittaLuciaL,
pubmed-author:MarucciAntonellaA,
pubmed-author:MastroiannoSandraS,
pubmed-author:MenzaghiClaudiaC,
pubmed-author:PandolfiAssuntaA,
pubmed-author:PellegriniFabioF,
pubmed-author:PerticoneFrancescoF,
pubmed-author:TrischittaVincenzoV
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pubmed:issnType |
Electronic
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pubmed:volume |
29
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1678-83
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19679831-Adult,
pubmed-meshheading:19679831-Blood Pressure,
pubmed-meshheading:19679831-Cells, Cultured,
pubmed-meshheading:19679831-Endothelial Cells,
pubmed-meshheading:19679831-European Continental Ancestry Group,
pubmed-meshheading:19679831-Female,
pubmed-meshheading:19679831-Humans,
pubmed-meshheading:19679831-Hypertension,
pubmed-meshheading:19679831-Insulin,
pubmed-meshheading:19679831-Insulin Resistance,
pubmed-meshheading:19679831-Male,
pubmed-meshheading:19679831-Middle Aged,
pubmed-meshheading:19679831-Nitric Oxide Synthase,
pubmed-meshheading:19679831-Phosphoric Diester Hydrolases,
pubmed-meshheading:19679831-Phosphorylation,
pubmed-meshheading:19679831-Polymorphism, Genetic,
pubmed-meshheading:19679831-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:19679831-Pyrophosphatases,
pubmed-meshheading:19679831-Receptor, Insulin,
pubmed-meshheading:19679831-Signal Transduction,
pubmed-meshheading:19679831-Systole
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pubmed:year |
2009
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pubmed:articleTitle |
ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells.
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pubmed:affiliation |
Endocrine Unit, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini 1, San Giovanni Rotondo, Italy. dnnwba@tin.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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