Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2009-11-20
pubmed:abstractText
The clinical features and outcome of small intestinal lymphoma remain unclear. We retrospectively analyzed 23 patients who had non-Hodgkin lymphoma with a small intestinal lesion. With a median follow-up of 37 months, the 5-year overall survival and failure-free survival (FFS) were 64% and 60%, respectively. In a univariate analysis, a worse performance status at the start of treatment and the occurrence of abdominal symptoms or perforation during treatment were associated with poor survival. Perforation often resulted in a dismal prognosis in patients with uncontrollable lymphoma, but not in patients with lymphoma in remission. The role of surgery in small intestinal lymphoma remains equivocal. In the current study, surgery before other therapies favorably influenced FFS, and all patients who underwent complete resection of the small intestinal lesion had extremely favorable results. Further studies are warranted to establish optimal therapeutic strategies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1029-2403
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1618-24
pubmed:meshHeading
pubmed-meshheading:19672778-Abdominal Pain, pubmed-meshheading:19672778-Adult, pubmed-meshheading:19672778-Aged, pubmed-meshheading:19672778-Aged, 80 and over, pubmed-meshheading:19672778-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:19672778-Combined Modality Therapy, pubmed-meshheading:19672778-Female, pubmed-meshheading:19672778-Follow-Up Studies, pubmed-meshheading:19672778-Gastrointestinal Hemorrhage, pubmed-meshheading:19672778-Humans, pubmed-meshheading:19672778-Ileal Neoplasms, pubmed-meshheading:19672778-Intestinal Obstruction, pubmed-meshheading:19672778-Intestinal Perforation, pubmed-meshheading:19672778-Japan, pubmed-meshheading:19672778-Jejunal Neoplasms, pubmed-meshheading:19672778-Lymphoma, Non-Hodgkin, pubmed-meshheading:19672778-Male, pubmed-meshheading:19672778-Middle Aged, pubmed-meshheading:19672778-Prognosis, pubmed-meshheading:19672778-Retrospective Studies, pubmed-meshheading:19672778-Survival Analysis, pubmed-meshheading:19672778-Treatment Outcome
pubmed:year
2009
pubmed:articleTitle
Clinical outcome in patients with small-intestinal non-Hodgkin lymphoma.
pubmed:affiliation
Division of Hematology, Department of Internal medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
pubmed:publicationType
Journal Article