Source:http://linkedlifedata.com/resource/pubmed/id/19670161
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-12-24
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pubmed:abstractText |
Bioactivity-directed fractionation of the extract of the mangrove endophytic fungus Talaromyces sp. ZH-154, which was isolated from the stem bark of Kandelia candel (L.) Druce, Rhizophoraceae, afforded two new metabolites, 7-epiaustdiol ( 1) and 8-O-methylepiaustdiol ( 2), together with the known compounds, stemphyperylenol ( 3), skyrin ( 4), secalonic acid A ( 5), emodin ( 6), and norlichexanthone ( 7). Their structures were elucidated on the basis of spectroscopic evidences including CD, MS, and 1D, 2D NMR techniques. The absolute configuration of 1 was unequivocally determined by single-crystal X-ray diffraction. All isolated compounds were evaluated for their antimicrobial and in vitro cytotoxic activities.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1439-0221
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pubmed:author | |
pubmed:copyrightInfo |
Georg Thieme Verlag KG Stuttgart . New York.
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pubmed:issnType |
Electronic
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
185-9
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pubmed:dateRevised |
2011-1-13
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pubmed:meshHeading |
pubmed-meshheading:19670161-Anthracenes,
pubmed-meshheading:19670161-Antineoplastic Agents,
pubmed-meshheading:19670161-Benzopyrans,
pubmed-meshheading:19670161-Cell Line, Tumor,
pubmed-meshheading:19670161-Crystallography, X-Ray,
pubmed-meshheading:19670161-Humans,
pubmed-meshheading:19670161-Magnetic Resonance Spectroscopy,
pubmed-meshheading:19670161-Molecular Structure,
pubmed-meshheading:19670161-Mycorrhizae,
pubmed-meshheading:19670161-Plant Bark,
pubmed-meshheading:19670161-Plant Stems,
pubmed-meshheading:19670161-Rhizophoraceae,
pubmed-meshheading:19670161-Talaromyces,
pubmed-meshheading:19670161-X-Ray Diffraction
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pubmed:year |
2010
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pubmed:articleTitle |
The bioactive metabolites of the mangrove endophytic fungus Talaromyces sp. ZH-154 isolated from Kandelia candel (L.) Druce.
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pubmed:affiliation |
School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou, China.
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pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
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