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pubmed-article:19663877pubmed:abstractTextPara-phenylenediamine (PPD) is a common contact sensitizer causing allergic contact dermatitis, a major skin problem. As PPD may need activation to become immunogenic, the balance between activation and/or detoxification processes may influence an individual's susceptibility. PPD is acetylated and the metabolites do not activate dendritic-like cells and T cells of PPD-sensitized individuals.lld:pubmed
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pubmed-article:19663877pubmed:articleTitlePara-phenylenediamine and allergic sensitization: risk modification by N-acetyltransferase 1 and 2 genotypes.lld:pubmed
pubmed-article:19663877pubmed:affiliationDepartment of Environmental Toxicology, University Trier, 54296 Trier, Germany. bloemeke@uni-trier.delld:pubmed
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