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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-10-27
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pubmed:abstractText |
Para-phenylenediamine (PPD) is a common contact sensitizer causing allergic contact dermatitis, a major skin problem. As PPD may need activation to become immunogenic, the balance between activation and/or detoxification processes may influence an individual's susceptibility. PPD is acetylated and the metabolites do not activate dendritic-like cells and T cells of PPD-sensitized individuals.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1365-2133
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
161
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1130-5
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:19663877-Acetylation,
pubmed-meshheading:19663877-Adolescent,
pubmed-meshheading:19663877-Adult,
pubmed-meshheading:19663877-Aged,
pubmed-meshheading:19663877-Aged, 80 and over,
pubmed-meshheading:19663877-Arylamine N-Acetyltransferase,
pubmed-meshheading:19663877-Child,
pubmed-meshheading:19663877-Dermatitis, Allergic Contact,
pubmed-meshheading:19663877-Female,
pubmed-meshheading:19663877-Genotype,
pubmed-meshheading:19663877-Humans,
pubmed-meshheading:19663877-Immunization,
pubmed-meshheading:19663877-Isoenzymes,
pubmed-meshheading:19663877-Male,
pubmed-meshheading:19663877-Middle Aged,
pubmed-meshheading:19663877-Phenylenediamines,
pubmed-meshheading:19663877-Polymorphism, Genetic,
pubmed-meshheading:19663877-Risk Factors,
pubmed-meshheading:19663877-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Para-phenylenediamine and allergic sensitization: risk modification by N-acetyltransferase 1 and 2 genotypes.
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pubmed:affiliation |
Department of Environmental Toxicology, University Trier, 54296 Trier, Germany. bloemeke@uni-trier.de
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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