Linked Life Data

19649649

Source:http://linkedlifedata.com/resource/pubmed/id/19649649

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-10-16
pubmed:abstractText
This study examined the effects of heavy resistance training on physiological acute exercise-induced fatigue (5 x 10 RM leg press) changes after two loading protocols with the same relative intensity (%) (5 x 10 RM(Rel)) and the same absolute load (kg) (5 x 10 RM(Abs)) as in pretraining in men (n = 12). Exercise-induced neuromuscular (maximal strength and muscle power output), acute cytokine and hormonal adaptations (i.e., total and free testosterone, cortisol, growth hormone (GH), insulin-like growth factor-1 (IGF-1), IGF binding protein-3 (IGFBP-3), interleukin-1 receptor antagonist (IL-1ra), IL-1beta, IL-6, and IL-10 and metabolic responses (i.e., blood lactate) were measured before and after exercise. The resistance training induced similar acute responses in serum cortisol concentration but increased responses in anabolic hormones of FT and GH, as well as inflammation-responsive cytokine IL-6 and the anti-inflammatory cytokine IL-10, when the same relative load was used. This response was balanced by a higher release of pro-inflammatory cytokines IL-1beta and cytokine inhibitors (IL-1ra) when both the same relative and absolute load was used after training. This enhanced hormonal and cytokine response to strength exercise at a given relative exercise intensity after strength training occurred with greater accumulated fatigue and metabolic demand (i.e., blood lactate accumulation). The magnitude of metabolic demand or the fatigue experienced during the resistance exercise session influences the hormonal and cytokine response patterns. Similar relative intensities may elicit not only higher exercise-induced fatigue but also an increased acute hormonal and cytokine response during the initial phase of a resistance training period.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1439-6327
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
107
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
397-409
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Cytokine and hormone responses to resistance training.
pubmed:affiliation
Studies, Research and Sport Medicine Center, Government of Navarra, 31005 Pamplona, Navarra, Spain. mikel.izquierdo@ceimd.org
pubmed:publicationType
Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't