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pubmed-article:19631980pubmed:abstractTextPreeclampsia is characterized by a systemic inflammatory response involving cytokines, chemokines, and anti-angiogenic factors such as sFLT-1. In many other inflammatory diseases related responses are triggered by toll-like receptor (TLR) stimulation. Therefore, we tested the hypothesis that TLR stimulation of a trophoblast cell line induces inflammatory mediator production and, in particular, production of the preeclampsia-related anti-angiogenic factor sFLT-1.lld:pubmed
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pubmed-article:19631980pubmed:articleTitleToll-like receptor-3 stimulation upregulates sFLT-1 production by trophoblast cells.lld:pubmed
pubmed-article:19631980pubmed:affiliationCritical Care Research Laboratories, Heart+Lung Institute, University of British Columbia, Vancouver V6Z 1Y6, Canada.lld:pubmed
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