Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2009-9-8
pubmed:abstractText
Preeclampsia is characterized by a systemic inflammatory response involving cytokines, chemokines, and anti-angiogenic factors such as sFLT-1. In many other inflammatory diseases related responses are triggered by toll-like receptor (TLR) stimulation. Therefore, we tested the hypothesis that TLR stimulation of a trophoblast cell line induces inflammatory mediator production and, in particular, production of the preeclampsia-related anti-angiogenic factor sFLT-1.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL5, http://linkedlifedata.com/resource/pubmed/chemical/Culture Media, Conditioned, http://linkedlifedata.com/resource/pubmed/chemical/FLT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Inflammation Mediators, http://linkedlifedata.com/resource/pubmed/chemical/Interferon Regulatory Factors, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6, http://linkedlifedata.com/resource/pubmed/chemical/Ligands, http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 3, http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptors, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor...
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1532-3102
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
774-9
pubmed:meshHeading
pubmed-meshheading:19631980-Analysis of Variance, pubmed-meshheading:19631980-Cell Line, pubmed-meshheading:19631980-Chemokine CCL5, pubmed-meshheading:19631980-Culture Media, Conditioned, pubmed-meshheading:19631980-Endothelial Cells, pubmed-meshheading:19631980-Female, pubmed-meshheading:19631980-Humans, pubmed-meshheading:19631980-Inflammation Mediators, pubmed-meshheading:19631980-Interferon Regulatory Factors, pubmed-meshheading:19631980-Interleukin-6, pubmed-meshheading:19631980-Ligands, pubmed-meshheading:19631980-NF-kappa B, pubmed-meshheading:19631980-Pre-Eclampsia, pubmed-meshheading:19631980-Pregnancy, pubmed-meshheading:19631980-Promoter Regions, Genetic, pubmed-meshheading:19631980-RNA, Messenger, pubmed-meshheading:19631980-Signal Transduction, pubmed-meshheading:19631980-Toll-Like Receptor 3, pubmed-meshheading:19631980-Toll-Like Receptors, pubmed-meshheading:19631980-Transfection, pubmed-meshheading:19631980-Trophoblasts, pubmed-meshheading:19631980-Up-Regulation, pubmed-meshheading:19631980-Vascular Endothelial Growth Factor Receptor-1
pubmed:year
2009
pubmed:articleTitle
Toll-like receptor-3 stimulation upregulates sFLT-1 production by trophoblast cells.
pubmed:affiliation
Critical Care Research Laboratories, Heart+Lung Institute, University of British Columbia, Vancouver V6Z 1Y6, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't