Linked Life Data

19631469

Source:http://linkedlifedata.com/resource/pubmed/id/19631469

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2009-10-5
pubmed:abstractText
The aim of this study was to investigate the efficacy of diminazene aceturate in the control of the infection by Trypanosoma evansi in cats. Fourteen animals were infected with 10(8) trypomastigote forms each and six were used as negative control (group A). Seven of the infected cats were used as positive control (group B) and seven were treated with diminazene aceturate (3.5 mg kg(-1)) for 5 consecutive days (group C). Biochemical and hematological parameters were evaluated during the experiment. Blood with anticoagulant was collected at day 49 post-inoculation and preserved in ethanol for DNA extraction. Samples were analyzed using PCR T. evansi-specific to assess the effectiveness of treatment. The treatment with diminazene aceturate had an efficacy of 85.7%. Alanine aminotransferase, gamma-glutamyltransferase, urea, and creatinine values remained within the normal physiological range in the treated cats. Hemogram was normalized in all the cured animals. Therefore, the therapy used is effective in controlling T. evansi in cats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1873-2550
pubmed:author
pubmed:issnType
Electronic
pubmed:day
28
pubmed:volume
165
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-50
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Diminazene aceturate in the control of Trypanosoma evansi infection in cats.
pubmed:affiliation
Department of Microbiology and Parasitology, Universidade Federal de Santa Maria, Camobi-9, Prédio 20, Sala 4232, Santa Maria, RS, Brazil. aleksandro_ss@yahoo.com.br
pubmed:publicationType
Journal Article