Linked Life Data

19630133

Source:http://linkedlifedata.com/resource/pubmed/id/19630133

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-7-22
pubmed:abstractText
The presence of dendritic cells in fish is studied with immunohistochemistry using a commercially available antibody developed against Langerin/CD207 present in human Langerhans cells. Langerin/CD207, a protein known to be associated with the development of Birbeck granules in human and murine systems, was found to be expressed within the cytoplasm of spleen and head kidney cells of Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss). Reactivity was also observed within a few number of cells within the head kidney of Atlantic salmon, but not observed in any other tissues examined. Immunohistochemical results showed Langerin/CD207 reactivity in the cytoplasm of cells in Atlantic salmon and rainbow trout comparable to reactivity seen in human Langerhans cells. The results in this study further corroborate the presence of dendritic cells with remarkable similarities to human Langerhans cells in the spleens and to a lesser extent in head kidney of salmonids.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1095-9947
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
365-8
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Langerin/CD207 positive dendritic-like cells in the haemopoietic tissues of salmonids.
pubmed:affiliation
Departments of Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown PEI C1A 4P3, Canada. JLovy@UPEI.ca
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't