Linked Life Data

19630092

Source:http://linkedlifedata.com/resource/pubmed/id/19630092

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-3-31
pubmed:abstractText
A simple and sensitive chemiluminescence (CL) method combined with flow injection technique was developed for the determination of naproxen. It was based upon the weak CL signal arising from the reaction of KIO(4) with H(2)O(2) being significantly increased by naproxen in the presence of europium(III) ion. The experimental conditions that affected the CL signal were carefully optimized and the CL reaction mechanism was briefly discussed. Under the optimum conditions, the increment of CL intensity was proportional to the concentration of naproxen ranging from 5.0 x 10(-8) to 5.0 x 10(-6) g/mL. The detection limit was 1 x 10(-8) g/mL naproxen and the relative standard deviation for 5.0 x 10(-7) g/mL naproxen solution was 2.1% (n = 11). The proposed method was applied to the determination of naproxen in tablets and in spiked human urine samples with satisfactory results.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1522-7243
pubmed:author
pubmed:copyrightInfo
Copyright (c) 2009 John Wiley & Sons, Ltd.
pubmed:issnType
Electronic
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
76-80
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:articleTitle
Chemiluminescence determination of naproxen based on europium(III)-sensitized KIO4-H2O2 reaction.
pubmed:affiliation
Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an, China. jxdu@snnu.edu.cn
pubmed:publicationType
Journal Article