Source:http://linkedlifedata.com/resource/pubmed/id/19620608
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2009-7-21
|
| pubmed:abstractText |
Individual variations in the course of Lewy body Parkinson disease (PD) are well known. Patients have been classified into different clinical subtypes to identify differences in the course among the subgroups. Several studies indicate that the outcome is more favorable in tremor dominant (TD) cases but others report no difference. A majority of progression studies are based on cross-sectional single point data or short-term clinical observations. The lack of longitudinally followed autopsy-confirmed PD cohort remains a major weakness in the literature. Biochemical studies of brain indicate most pronounced abnormalities in akinetic/rigid (AR) and the least in TD cases. We postulate that PD course in these subtypes is concordant with the biochemical findings.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
1526-632X
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:day |
21
|
| pubmed:volume |
73
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
206-12
|
| pubmed:meshHeading |
pubmed-meshheading:19620608-Age of Onset,
pubmed-meshheading:19620608-Aged,
pubmed-meshheading:19620608-Aged, 80 and over,
pubmed-meshheading:19620608-Akinetic Mutism,
pubmed-meshheading:19620608-Autopsy,
pubmed-meshheading:19620608-Brain,
pubmed-meshheading:19620608-Brain Chemistry,
pubmed-meshheading:19620608-Cohort Studies,
pubmed-meshheading:19620608-Comorbidity,
pubmed-meshheading:19620608-Dementia,
pubmed-meshheading:19620608-Disease Progression,
pubmed-meshheading:19620608-Female,
pubmed-meshheading:19620608-Follow-Up Studies,
pubmed-meshheading:19620608-Humans,
pubmed-meshheading:19620608-Longitudinal Studies,
pubmed-meshheading:19620608-Male,
pubmed-meshheading:19620608-Middle Aged,
pubmed-meshheading:19620608-Muscle Rigidity,
pubmed-meshheading:19620608-Parkinson Disease,
pubmed-meshheading:19620608-Time Factors,
pubmed-meshheading:19620608-Tremor
|
| pubmed:year |
2009
|
| pubmed:articleTitle |
Course in Parkinson disease subtypes: A 39-year clinicopathologic study.
|
| pubmed:affiliation |
Division of Neurology, Department of Pathology, Saskatoon Health Region/University of Saskatchewan, Canada.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|