Source:http://linkedlifedata.com/resource/pubmed/id/19601397
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-7-15
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pubmed:abstractText |
The effects of oral and topical application of Calendula officinalis flower extract on excision wounds made in rats were checked. The parameters assessed were the days needed for re-epithelization and percentage of wound closure. The hydroxy proline and hexosamine content in the granuloma tissue of the wound was also measured. The percentage of wound closure was 90.0% in the extract-treated group, whereas the control group showed only 51.1% on the eighth day of wounding (p < .01). The days needed for re-epithelization were 17.7 for the control animals; extract treatment at a dose of 20 or 100 mg/kg b.wt reduced the period to 14 and 13 days, respectively. A significant increase was observed in the hydroxy proline and hexosamine content in the extract-treated group compared with the untreated animals. The data indicate potent wound healing activity ofC. officinalis extract.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antioxidants,
http://linkedlifedata.com/resource/pubmed/chemical/Carotenoids,
http://linkedlifedata.com/resource/pubmed/chemical/Hexosamines,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyproline,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Extracts
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pubmed:status |
MEDLINE
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pubmed:issn |
0792-6855
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
73-9
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pubmed:meshHeading |
pubmed-meshheading:19601397-Animals,
pubmed-meshheading:19601397-Antioxidants,
pubmed-meshheading:19601397-Calendula,
pubmed-meshheading:19601397-Carotenoids,
pubmed-meshheading:19601397-Female,
pubmed-meshheading:19601397-Flowers,
pubmed-meshheading:19601397-Hexosamines,
pubmed-meshheading:19601397-Hydroxyproline,
pubmed-meshheading:19601397-Plant Extracts,
pubmed-meshheading:19601397-Rats,
pubmed-meshheading:19601397-Rats, Wistar,
pubmed-meshheading:19601397-Wound Healing
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pubmed:year |
2009
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pubmed:articleTitle |
Wound healing activity of flower extract of Calendula officinalis.
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pubmed:affiliation |
Department of Biochemistry, Amala Cancer Research Centre Amala Nagar, Thrissur-680555, Kerala, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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