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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-9-2
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pubmed:abstractText |
The aims of this study were to validate stiffness estimates of a phantom undergoing cyclic deformation obtained using a multiphase magnetic resonance elastography (MRE) imaging sequence by comparison with those obtained using a single-phase MRE sequence and to quantify the stability of the multiphase-derived stiffness estimates as a function of deformation frequency and imaging parameters. A spherical rubber shell of 10 cm diameter and 1 cm thickness was connected to a computerized flow pump to produce cyclic pressure variations within the phantom. The phantom was imaged at cyclic pressures between 18-72 bpm using single-phase and multiphase MRE acquisitions. The shear stiffness of the phantom was resolved using a spherical shell wave inversion algorithm. Shear stiffness was averaged over the slice of interest and plotted against pressure within the phantom. A linear correlation was observed between stiffness and pressure. Good correlation (R(2) = 0.98) was observed between the stiffness estimates obtained using the standard single-phase and the multiphase pulse sequences. Stiffness estimates obtained using multiphase MRE were stable when the fraction of the deformation period required for acquisition of a single image was not greater than 42%. The results demonstrate the potential of multiphase MRE technique for imaging dynamic organs, such as the heart.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-11731304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-12618225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-15678538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-16014610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-16051038,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-16614298,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-17260354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-17614101,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-17729336,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-17916548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-18065839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-18923255,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-1987592,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-2405455,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-4269516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-6848219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-8682057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-8722827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19572388-9323091
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1522-2594
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
691-8
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:19572388-Algorithms,
pubmed-meshheading:19572388-Elasticity,
pubmed-meshheading:19572388-Elasticity Imaging Techniques,
pubmed-meshheading:19572388-Heart,
pubmed-meshheading:19572388-Humans,
pubmed-meshheading:19572388-Image Enhancement,
pubmed-meshheading:19572388-Image Interpretation, Computer-Assisted,
pubmed-meshheading:19572388-Magnetic Resonance Imaging, Cine,
pubmed-meshheading:19572388-Phantoms, Imaging,
pubmed-meshheading:19572388-Reproducibility of Results,
pubmed-meshheading:19572388-Sensitivity and Specificity,
pubmed-meshheading:19572388-Stress, Mechanical
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pubmed:year |
2009
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pubmed:articleTitle |
Evaluation of a rapid, multiphase MRE sequence in a heart-simulating phantom.
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pubmed:affiliation |
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
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pubmed:publicationType |
Journal Article,
Evaluation Studies,
Research Support, N.I.H., Extramural
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