Source:http://linkedlifedata.com/resource/pubmed/id/19561008
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-6-29
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pubmed:abstractText |
Ratios of young platelets or reticulated platelets can be routinely obtained as an immature platelet fraction (IPF) with the XE-2100 automated hematology analyzer (Sysmex, Kobe, Japan). We combined IPF analysis of 31 patients with myelodysplastic syndrome (MDS) with a complete blood count, a bone marrow examination, and a chromosome analysis. The patients with >40 x 10(9)/L platelets were classified as group A, and those with > or =40 x 10(9)/L were placed in group B. The 2 groups were subclassified as A1 or B1 for patients with an IPF of <10% and as A2 or B2 for those with an IPF > or =10%. Categories A1, A2, B1, and B2 comprised 12 patients, 6 patients, 7 patients, and 6 patients, respectively. Patients with a relatively high IPF (>10%) (category A2 or B2) showed distinctive characteristics. Group B2 showed a higher frequency of chromosomal abnormalities than B1 (P = .029), and group A2 tended to show a higher incidence of clinical improvement than A1 (P = .08). IPF determination may be clinically useful for the assessment of prognosis for MDS patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1523-6528
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pubmed:author |
pubmed-author:ImaiJunkoJ,
pubmed-author:IsonoSetsukiS,
pubmed-author:KubotaYoshitsuguY,
pubmed-author:NishizawaAkihikoA,
pubmed-author:NomuraTsutomuT,
pubmed-author:NumataKeikoK,
pubmed-author:SaigoKatsuyasuK,
pubmed-author:TakadaMasafumiM,
pubmed-author:TakenokuchiMarikoM,
pubmed-author:TaniokaHiroakiH,
pubmed-author:YoshiokaToyoT,
pubmed-author:ZenibayashiMasakoM
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pubmed:issnType |
Electronic
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
13-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19561008-Adolescent,
pubmed-meshheading:19561008-Adult,
pubmed-meshheading:19561008-Aged,
pubmed-meshheading:19561008-Aged, 80 and over,
pubmed-meshheading:19561008-Blood Cell Count,
pubmed-meshheading:19561008-Blood Platelets,
pubmed-meshheading:19561008-Bone Marrow Examination,
pubmed-meshheading:19561008-Chromosome Aberrations,
pubmed-meshheading:19561008-Clinical Laboratory Techniques,
pubmed-meshheading:19561008-Female,
pubmed-meshheading:19561008-Humans,
pubmed-meshheading:19561008-Male,
pubmed-meshheading:19561008-Middle Aged,
pubmed-meshheading:19561008-Myelodysplastic Syndromes,
pubmed-meshheading:19561008-Platelet Count,
pubmed-meshheading:19561008-Prognosis,
pubmed-meshheading:19561008-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Usefulness of immature platelet fraction for the clinical evaluation of myelodysplastic syndromes.
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pubmed:affiliation |
Faculty of Pharmacological Science, Himeji Dokkyo University, Himeji, Japan. ksaigo@himeji-du.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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