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pubmed-article:19557126pubmed:abstractTextTechnologies based on DNA microarrays have the potential to provide detailed information on genomic aberrations in tumor cells. In practice a major obstacle for quantitative detection of aberrations is the heterogeneity of clinical tumor tissue. Since tumor tissue invariably contains genetically normal stromal cells, this may lead to a failure to detect aberrations in the tumor cells.lld:pubmed
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pubmed-article:19557126pubmed:articleTitleQuantification of normal cell fraction and copy number neutral LOH in clinical lung cancer samples using SNP array data.lld:pubmed
pubmed-article:19557126pubmed:affiliationDepartment of Medical Sciences, Uppsala University, Uppsala, Sweden.lld:pubmed
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