Source:http://linkedlifedata.com/resource/pubmed/id/19555248
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
2009-9-24
|
pubmed:abstractText |
We tested the hypothesis that the increases in the porosity of the skin during iontophoresis would not significantly increase the transport of peptides due to the small size of electrically induced pores. To investigate this mechanistically, we used human epidermal membrane under constant voltage conditions, applying the Nernst-Planck equation to the transport of a small ionic solute, tetraethylammonium bromide (TEAB), and a model peptide, luteinizing hormone releasing hormone.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1520-5762
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:volume |
35
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1201-9
|
pubmed:meshHeading |
pubmed-meshheading:19555248-Administration, Cutaneous,
pubmed-meshheading:19555248-Biological Transport,
pubmed-meshheading:19555248-Electric Conductivity,
pubmed-meshheading:19555248-Epidermis,
pubmed-meshheading:19555248-Female,
pubmed-meshheading:19555248-Humans,
pubmed-meshheading:19555248-Iontophoresis,
pubmed-meshheading:19555248-Luteinizing Hormone,
pubmed-meshheading:19555248-Models, Biological,
pubmed-meshheading:19555248-Permeability,
pubmed-meshheading:19555248-Porosity,
pubmed-meshheading:19555248-Tetraethylammonium
|
pubmed:year |
2009
|
pubmed:articleTitle |
The influence of porosity changes in human epidermal membrane during iontophoresis on the permeability enhancement of a model peptide.
|
pubmed:affiliation |
Division of Pharmaceutical Sciences, College of Pharmacy, University of New Mexico, Albuquerque, NM 87131, USA. hsmyth@salud.unm.edu
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|