Source:http://linkedlifedata.com/resource/pubmed/id/19549672
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-8-12
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pubmed:abstractText |
Acanthamoebae can cause infections of several organs, including eye, skin, lung and brain. Except for Acanthamoeba keratitis, these infections are linked to immunodeficiency. Treatment is generally problematic, due to the lack of sufficiently effective and also easily manageable drugs. In a previous study we discovered that miltefosine (hexadecylphosphocholine) is highly active against Acanthamoeba spp. in vitro. The aim of the current study was to evaluate the suitability of miltefosine for the topical treatment of Acanthamoeba infections.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1460-2091
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
539-45
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pubmed:meshHeading |
pubmed-meshheading:19549672-Acanthamoeba,
pubmed-meshheading:19549672-Animals,
pubmed-meshheading:19549672-Antiprotozoal Agents,
pubmed-meshheading:19549672-Candida albicans,
pubmed-meshheading:19549672-Drug Stability,
pubmed-meshheading:19549672-Drug Storage,
pubmed-meshheading:19549672-Humans,
pubmed-meshheading:19549672-Phosphorylcholine,
pubmed-meshheading:19549672-Skin Diseases,
pubmed-meshheading:19549672-Staphylococcus
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pubmed:year |
2009
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pubmed:articleTitle |
Anti-acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent.
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pubmed:affiliation |
Department of Medical Parasitology, Institute of Hygiene, Medical University of Vienna, 1095 Vienna, Austria. julia.walochnik@meduniwien.ac.at
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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