Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-8-12
pubmed:abstractText
Acanthamoebae can cause infections of several organs, including eye, skin, lung and brain. Except for Acanthamoeba keratitis, these infections are linked to immunodeficiency. Treatment is generally problematic, due to the lack of sufficiently effective and also easily manageable drugs. In a previous study we discovered that miltefosine (hexadecylphosphocholine) is highly active against Acanthamoeba spp. in vitro. The aim of the current study was to evaluate the suitability of miltefosine for the topical treatment of Acanthamoeba infections.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1460-2091
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
539-45
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Anti-acanthamoeba efficacy and toxicity of miltefosine in an organotypic skin equivalent.
pubmed:affiliation
Department of Medical Parasitology, Institute of Hygiene, Medical University of Vienna, 1095 Vienna, Austria. julia.walochnik@meduniwien.ac.at
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't