rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1991-12-2
|
pubmed:abstractText |
Four protein isoforms of the human CD46 molecule (MCP) have been identified using rabbit antisera against synthetic peptides corresponding to predicted cytoplasmic carboxyl-terminal sequences. Two different cytoplasmic tails, CD46 CYT 1 and CD46 CYT 2, were detected in CD46 molecules isolated from almost every cell type examined. Bands of 56 and 66 kDa were obtained from SDS-PAGE analyses of various cell types with both CYT 1 and CYT 2 antisera, which indicated that the size polymorphism of the CD46 molecule is not due to variations in the cytoplasmic tail and that each species contained two different sized molecules.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0006-291X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
31
|
pubmed:volume |
180
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1091-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1953714-Amino Acid Sequence,
pubmed-meshheading:1953714-Animals,
pubmed-meshheading:1953714-Antibodies,
pubmed-meshheading:1953714-Antigen-Antibody Complex,
pubmed-meshheading:1953714-Antigens, CD,
pubmed-meshheading:1953714-Antigens, CD46,
pubmed-meshheading:1953714-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:1953714-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:1953714-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1953714-Humans,
pubmed-meshheading:1953714-Membrane Glycoproteins,
pubmed-meshheading:1953714-Molecular Sequence Data,
pubmed-meshheading:1953714-Peptides,
pubmed-meshheading:1953714-Rabbits
|
pubmed:year |
1991
|
pubmed:articleTitle |
Identification of four different CD46 (MCP) molecules with anti-peptide antibodies.
|
pubmed:affiliation |
Austin Research Institute, Austin Hospital, Heidelberg, Victoria, Australia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|