rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2009-6-18
|
pubmed:abstractText |
Sema4D/CD100 is a type of class 4 semaphorin, exhibiting crucial roles in growth cone guidance in developing neurons. Sema4D is widely expressed throughout the central nervous system in embryonic mouse brain, and is selectively localized to oligodendrocytes and myelin in the postnatal brain. However, direct evidence of the actual involvement of Sema4D in the neuronal network development crucial for neurobehavioral performance is still lacking. The present study therefore examined whether Sema4D deficiency leads to abnormal behavioral development.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0317-1671
|
pubmed:author |
pubmed-author:IsoHiroyukiH,
pubmed-author:KikutaniHitoshiH,
pubmed-author:KohsakaAkiraA,
pubmed-author:KumanogohAtsushiA,
pubmed-author:MaedaMasanobuM,
pubmed-author:MiyajimaMasayasuM,
pubmed-author:TakeuchiNorikoN,
pubmed-author:TanakaTetsujiT,
pubmed-author:WakiHidefumiH,
pubmed-author:XXX,
pubmed-author:YukawaKazunoriK
|
pubmed:issnType |
Print
|
pubmed:volume |
36
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
349-55
|
pubmed:meshHeading |
pubmed-meshheading:19534337-Animals,
pubmed-meshheading:19534337-Avoidance Learning,
pubmed-meshheading:19534337-Behavior, Animal,
pubmed-meshheading:19534337-Calcium-Binding Protein, Vitamin D-Dependent,
pubmed-meshheading:19534337-Cerebellum,
pubmed-meshheading:19534337-Exploratory Behavior,
pubmed-meshheading:19534337-Locomotion,
pubmed-meshheading:19534337-Maze Learning,
pubmed-meshheading:19534337-Mice,
pubmed-meshheading:19534337-Mice, Knockout,
pubmed-meshheading:19534337-Motor Activity,
pubmed-meshheading:19534337-Psychomotor Performance,
pubmed-meshheading:19534337-Reaction Time,
pubmed-meshheading:19534337-Rotarod Performance Test,
pubmed-meshheading:19534337-Semaphorins,
pubmed-meshheading:19534337-Spatial Behavior,
pubmed-meshheading:19534337-Time Factors
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pubmed:year |
2009
|
pubmed:articleTitle |
Sema4D/CD100 deficiency leads to superior performance in mouse motor behavior.
|
pubmed:affiliation |
Department of Physiology, Faculty of Pharmacy, Meijo University, Tempaku-ku, Nagoya, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|