Linked Life Data

19518480

Source:http://linkedlifedata.com/resource/pubmed/id/19518480

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 1
pubmed:dateCreated
2009-6-12
pubmed:abstractText
We study the kinetics of growing cell populations by means of a kinetic Monte Carlo method. By applying the same growth mechanism to a two-dimensional (2D) and a three-dimensional (3D) model, and making direct comparison with experimental studies, we show that both models exhibit similar behavior. Based on this we propose a method for establishment of a mapping between the 2D and 3D results. Additionally, we present an analytic approach to obtain the time evolution, and show in case of the 3D model how synchronization effects can influence the growth kinetics. Finally, we compare the results of our models to experimental data of the growth kinetics of 2D monolayers and 3D NIH3T3 xenografts in mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1539-3755
pubmed:author
pubmed:issnType
Print
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
051907
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Comparing the growth kinetics of cell populations in two and three dimensions.
pubmed:affiliation
Institut für Theoretische Physik, Technische Universität Berlin, D-10623 Berlin, Germany. radszuweit@itp.physik.tu-berlin.de
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't