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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-10-20
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pubmed:abstractText |
Current positron emission tomography (PET) radioligands for detection of Abeta amyloid in Alzheimer's disease (AD) are not ideal for quantification. To improve the signal to noise ratio we have developed the radioligand [(11)C]AZD2184 and report here the first clinical evaluation.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1619-7089
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pubmed:author |
pubmed-author:AnderssonJanJ,
pubmed-author:CselényiZsoltZ,
pubmed-author:FardeLarsL,
pubmed-author:Freund-LeviYvonneY,
pubmed-author:HalldinChristerC,
pubmed-author:JönhagenMaria EriksdotterME,
pubmed-author:JulinPerP,
pubmed-author:NybergSvanteS,
pubmed-author:OlssonHansH,
pubmed-author:SvenssonSamuelS,
pubmed-author:VarnäsKatarinaK
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pubmed:issnType |
Electronic
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1859-63
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19495746-Adult,
pubmed-meshheading:19495746-Aged,
pubmed-meshheading:19495746-Alzheimer Disease,
pubmed-meshheading:19495746-Aminopyridines,
pubmed-meshheading:19495746-Amyloid beta-Peptides,
pubmed-meshheading:19495746-Benzothiazoles,
pubmed-meshheading:19495746-Carbon Radioisotopes,
pubmed-meshheading:19495746-Case-Control Studies,
pubmed-meshheading:19495746-Female,
pubmed-meshheading:19495746-Humans,
pubmed-meshheading:19495746-Male,
pubmed-meshheading:19495746-Middle Aged,
pubmed-meshheading:19495746-Positron-Emission Tomography,
pubmed-meshheading:19495746-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Detection of amyloid in Alzheimer's disease with positron emission tomography using [11C]AZD2184.
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pubmed:affiliation |
AstraZeneca R&D, Neuroscience Therapy Area, 151 85 Södertälje, Sweden. svante.nyberg@astrazeneca.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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