Linked Life Data

19489308

Source:http://linkedlifedata.com/resource/pubmed/id/19489308

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-6-3
pubmed:abstractText
By the open-field behavior, August rats were more resistant to acute hypoxia than Wistar rats. Hypoxic activation of the immune system was more pronounced in August rats. As differentiated from Wistar rats, the stress-limiting NO system in August rats was not suppressed during hypoxia. The effectiveness and resistance of this system to hypoxia were higher in August rats. Behavioral changes in Wistar rats under hypoxic conditions were accompanied by activation of HSP32 synthesis in blood leukocytes. This protein serves as an indicator of oxidative stress (i.e. adverse factor in hypoxia). August rats were more resistant to behavioral disturbances in hypoxia than Wistar rats. HSP32 synthesis in leukocytes from August rats was not impaired under hypoxic conditions. Our results indicate that variations in HSP32 synthesis in peripheral blood leukocytes can be considered as a matter of for resistance to acute hypoxia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0007-4888
pubmed:author
pubmed:issnType
Print
pubmed:volume
146
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
411-4
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Specific response of the organism and blood leukocytes in rats of different genetic strains to hypoxia.
pubmed:affiliation
Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia. niiopp@masil.ru
pubmed:publicationType
Journal Article